Pneumatosis intestinalis in acute mesenteric ischemia
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616.1-005.4-089 (1)
Патология сердечно-сосудистой системы. Сердечно-сосудистые заболевания (1025)
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GHIDIRIM, Gheorghe, MISHIN, Igor, CRĂCIUN, Ion, CUŢITARI, Irina. Pneumatosis intestinalis in acute mesenteric ischemia. In: Moldovan Medical Journal, 2018, nr. 61(S_RMI), p. 65. ISSN 2537-6373.
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Moldovan Medical Journal
Numărul 61(S_RMI) / 2018 / ISSN 2537-6373 /ISSNe 2537-6381

Pneumatosis intestinalis in acute mesenteric ischemia

CZU: 616.1-005.4-089

Pag. 65-65

Ghidirim Gheorghe1, Mishin Igor12, Crăciun Ion1, Cuţitari Irina1
 
1 ”Nicolae Testemițanu” State University of Medicine and Pharmacy,
2 Emergency Institute of Medicine
 
 
Disponibil în IBN: 20 mai 2024


Rezumat

Background: One of the radiological signs of acute arterial mesenteric ischemia (AMI) according to data of Multi-spiral Computed Tomography with angiography (MCTA) is pneumatosis intestinalis (PI). Taking into consideration absence of reliable information on the pathophysiology of PI, we performed a comparison of radiological data and morphological studies of the resected bowel wall segments. Material and methods: We analyzed MCTA images of 15 patients with arterial AMI (men-9, women-6; average age – 71.1±3.5 years (95% CI: 63.64–78.49). Results: PI was determined in all cases of AMI: type I (bubbly-like) was diagnosed more frequently (p<0.01) than type II (semilunar) and constituted 11(73.3%) vs. 4(26.7%) cases, respectively. During histological evaluation of bowel wall tissues, a number of particularities of these phenomena were revealed: (1) PI in all cases of AMI was associated with necrosis and desquamation of bowel mucosa; (2) morphologically they have a “honeycomb” appearance and are localized predominantly in perivascular areas; (3) the pattern of spreading – from mucosa to serosa layer, distinguish it from “benign” forms of PI. Also, it was determined that type I PI was associated with transmural necrosis of the bowel wall in 63.6% cases, whereas in type II PI – in 100% cases (p<0.05). Diagnostic value of this sign (PI) in arterial AMI constituted: Sе, Sp, PPV, NPV=100%. Conclusions: MCTA should be considered a method of choice for diagnosis of AMI. PI should be considered as a specific radiological sign of AMI. PI type II is associated in all the cases with transmural bowel wall necrosis.

Cuvinte-cheie
computed tomography, acute mesenteric ischemia, pneumatosis intestinalis

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<dc:creator>Ghidirim, G.P.</dc:creator>
<dc:creator>Mişin, I.V.</dc:creator>
<dc:creator>Crăciun, I.</dc:creator>
<dc:creator>Cuţitari, I.V.</dc:creator>
<dc:date>2018-06-04</dc:date>
<dc:description xml:lang='en'><p>Background: One of the radiological signs of acute arterial mesenteric ischemia (AMI) according to data of Multi-spiral Computed Tomography with angiography (MCTA) is pneumatosis intestinalis (PI). Taking into consideration absence of reliable information on the pathophysiology of PI, we performed a comparison of radiological data and morphological studies of the resected bowel wall segments. Material and methods: We analyzed MCTA images of 15 patients with arterial AMI (men-9, women-6; average age &ndash; 71.1&plusmn;3.5 years (95% CI: 63.64&ndash;78.49). Results: PI was determined in all cases of AMI: type I (bubbly-like) was diagnosed more frequently (p&lt;0.01) than type II (semilunar) and constituted 11(73.3%) vs. 4(26.7%) cases, respectively. During histological evaluation of bowel wall tissues, a number of particularities of these phenomena were revealed: (1) PI in all cases of AMI was associated with necrosis and desquamation of bowel mucosa; (2) morphologically they have a &ldquo;honeycomb&rdquo; appearance and are localized predominantly in perivascular areas; (3) the pattern of spreading &ndash; from mucosa to serosa layer, distinguish it from &ldquo;benign&rdquo; forms of PI. Also, it was determined that type I PI was associated with transmural necrosis of the bowel wall in 63.6% cases, whereas in type II PI &ndash; in 100% cases (p&lt;0.05). Diagnostic value of this sign (PI) in arterial AMI constituted: Sе, Sp, PPV, NPV=100%. Conclusions: MCTA should be considered a method of choice for diagnosis of AMI. PI should be considered as a specific radiological sign of AMI. PI type II is associated in all the cases with transmural bowel wall necrosis.</p></dc:description>
<dc:source>Moldovan Medical Journal S_RMI (61) 65-65</dc:source>
<dc:subject>computed tomography</dc:subject>
<dc:subject>acute mesenteric ischemia</dc:subject>
<dc:subject>pneumatosis intestinalis</dc:subject>
<dc:title>Pneumatosis intestinalis in acute mesenteric ischemia</dc:title>
<dc:type>info:eu-repo/semantics/article</dc:type>
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