The basis for positive social and economic transformations is the scientifi c and technological progress, in which the scientifi c research is focusing mainly on systemic solutions for general human and social problems that should contribute to economic development. Economic growth does not mean also economic development. The rapid growth of GDP can not be achieved with traditional management that aims at adapting to the extern environment. In the management of research and development, as well as in the classic one, it is necessary to introduce synergistic management that is the management technology of development at various levels ofsocioeconomic systems. Synergistic management is focused on accelerated development and breakthrough in socio-economic systems, including scientifi c research, through creation of synergistic effects of new research, innovation and economic media. It is imperative for Moldova the development of innovative economic sector and its orientation to the real needs of the market; optimization of R