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SM ISO690:2012 CABAC-POGOREVICI, Irina, REVENCO, Valeriu. COVID-19 infection and heart failure events. In: Revista de Ştiinţe ale Sănătăţii din Moldova, 2022, nr. 3 An.1(29), p. 179. ISSN 2345-1467. |
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Revista de Ştiinţe ale Sănătăţii din Moldova | ||||||
Numărul 3 An.1(29) / 2022 / ISSN 2345-1467 | ||||||
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CZU: 616.98:578.834+616.12-008.46-036.1 | ||||||
Pag. 179-179 | ||||||
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Background. COVID-19 pandemic has an impact on HF management, possibly leading to an increase in HF mortality, while history of HF is a risk factor for a more severe clinical course of COVID-19. Thus, the aim of our study is to analyze the complex interconnection between the COVID-19 and heart failure events. Material and methods. The research included 89 COVID-19 patients, admitted to the cardiology department 18-91 years, the mean age being of 67,23 ± 13,20 years, whereas 47% (42 pts) were men and 53% (47 pts) were women. Physical examination, ECG and echocardiography, laboratory parameters were collected: general blood count, natriuretic peptides, aspartate aminotransferase (AST), alanine aminotransferase (ALT), albumin, creatinine, serum sodium, and potassium, D-dimers, and INR. Results. Of all patients in the CVDRF (cardiovascular disease risk factors) cohort, 13 (15%) patients experienced, HF events at admission or during hospitalization, of which 40 (46%) patients in the HF subgroup and 7 (8%) in the nonHF subgroup, the latter accounting for 40% of all observed HF events. In the CVDRF cohort, patients with an HF event were at a two-fold increased risk for in-hospital mortality compared with those without HF events, p < 0.001, OR 3.10 [2.24–4.29]), even after adjustment for age, sex, risk factors, and co-morbidities. Interaction for HF events and age was significant (p = 0.023). Age, CV diseases, CV risk factors, history of HF, atrial fibrillation, and CKD were significantly associated with HF events. Conclusion. This study demonstrates a higher mortality for hospitalized COVID-19 patients with HF compared with patients without HF, even after adjustment for other conditions and co-morbidities. |
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Cuvinte-cheie heart failure, SARS-CoV-2, risk factors, insuficienţă cardiacă, SARS-CoV-2, factori de risc |
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