Introduction: The policy of building information society in the Republic of Moldova is an integral part of the state policy, being developed and regulated by the Government of Moldova to ensure public access to medical services and strengthen the monitoring, evaluation and decision-making capacity in providing the population with quality health services [1]. By the GD no. 632 of June 08, 2004 on approval of the policy of building information society in the Republic of Moldova and the GD no. 1128 of October 14, 2004 on approval of the Health Integrated Information System, the Moldovan Government argued that the XXI century economy and the health system as a component cannot be conceived without an information infrastructure, regulating the development goals of the Information Society. By the Joint Order no. 412/127/125/185-A of November 06, 2007 on approval of the Strategic Plan for the development of the National Health Information System, the Ministry of Health, jointly with the Ministry of Information Development, the National Bureau of Statistics and the National Health Insurance Company, has approved the Strategic Development Plan of the National Health Information System for the period 2008-2017. The strategic development goal is to develop NHIS in order to improve the supervision of the health system to achieve the strategic objectives of the health system [2,3]. The National Health Policy (GD no. 886 of August 06, 2007) and the Development Strategy of the Health System for 2008-2017 (GD no. 1471 of December 24, 2007) set as priority direction the strengthening of the monitoring and evaluation capacity in the health system by harmonizing the architecture, the technological platforms and the standards of the National Health Information System. The Ministry of Health is currently developing the eHealth strategy, which will help improve the operation and provision of health services, create mechanisms to manage, monitor and evaluate the performance and ensure public access to medical services. Materials and methods: Strategic direction cannot be achieved today without managerial capacities of quick adaptability and prompt managerial decisions aimed at achieving the proposed goal. IMSP CNŞPMU records annually 68-72 thousand appeals in the Emergency Medicine Department, from 23.5 to 24.5 thousand patients treated in clinic, 130-140 thousand outpatient visits in traumatology and orthopedics wards and 256260 thousand requests fulfilled by the Medical Emergency Service in Chisinau because of surgical emergencies. Since 2008, the IMSP CNŞPMU operates the «Hippocrates» Integrated Information System (HIIS). It is designed to facilitate the management of all medical and administrative information in the clinic and improve the quality of care provided [2]. The system is web-based and is compatible with any information system that works or can be implemented in the health system. HIIS meets the MoH and NHIC requirements regarding the medical, accounting and personnel statistical records [3]. Conclusions: Following the changes in the data handling, the content and ways of achieving the tasks, the managerial approaches have changed. The improvement of managers by acquiring and developing knowledge, methods, informatics skills in order to harness at a higher level the potential of computers has a very important role. At the same time it ensures a high accuracy of information processing, increasing also the degree of data handling. HIIS provides the manager and the management with the possibility to solve at a higher level most of the problems facing the institution. HIIS allows adequate solving of some types of problems involving a large number of complex and dynamic statistical and medical data, such as those related to forecasting the evolution of the curative and prophylactic process, the scheduling of activity in circumstances of high complexity and statistical reporting, whose achievement is impossible without an integrated information system.