Assessment of climate favorability for grapevine culture in Republic of Moldova. The knowledge regarding the impact of climate change on grapevine are relatively few, especially since researches have revealed obvious changes in the development of plant physiological and biochemical processes, with particular consequences on progress and duration of grapevine vegetative and ripening main phenophase. Grapevine is sensitive to the environmental conditions agricultural crop and its harvest and quality is obtained within territories with specific climatic characteristics. According to the data during the years 1980-2011, climatic parameters have undergone some changes. In this regard it is necessary to assess the climate suitability. In the context of optimal grapevine crop development, during the last century were designed a series of climatic indices which contain different variables. The purpose of calculation climatic indices is to determine the optimal limit standards of development.