Background. The risk of adverse perinatal outcomes is significantly high in pregnant women with intrahepatic cholestasis of pregnancy. Aim. Assessment and analysis of the characteristics of the course of pregnancy and delivery, the incidence and structure of perinatal morbidity among women with intrahepatic cholestasis of pregnancy. Materials and methods. The study was based on a retrospective case-control study, which included 205 women aged 17–43 years. They were divided into 2 groups depending on the complications of intrahepatic cholestasis of pregnancy Statistical data were processed using IBM SPSS Statistics V21.0 software. Results. The women, whose pregnancies were complicated by intrahepatic cholestasis of pregnancy, had an increased incidence of iron deficiency anemia, cesarean sections and needed longer hospital stay. The assessment of perinatal outcomes showed high rates of respiratory distress syndrome in neonates born to mothers with intrahepatic cholestasis of pregnancy. Conclusion. The study revealed that intrahepatic cholestasis of pregnancy has adverse impact on perinatal outcomes, showed rising rates of preterm birth, neonatal respiratory distress syndrome and cesarean section. This correlates with the data in the published scientific literature.