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<creators>
<creator>
<creatorName>Bernaz, E.P.</creatorName>
<affiliation>IMSP Institutul de Medicină Urgentă, Moldova, Republica</affiliation>
</creator>
</creators>
<titles>
<title xml:lang='en'>Evaluation of antibiotics consumption in therapeutic intensive care department</title>
</titles>
<publisher>Instrumentul Bibliometric National</publisher>
<publicationYear>2016</publicationYear>
<relatedIdentifier relatedIdentifierType='ISSN' relationType='IsPartOf'>1875-0666</relatedIdentifier>
<subjects>
<subject>Antibiotics</subject>
<subject>defined daily dose</subject>
<subject>consumption</subject>
<subject>rational use</subject>
<subject>hospitals</subject>
<subject schemeURI='http://udcdata.info/' subjectScheme='UDC'>614.253.1:615.33(478)</subject>
</subjects>
<dates>
<date dateType='Issued'>2016-04-28</date>
</dates>
<resourceType resourceTypeGeneral='Text'>Journal article</resourceType>
<descriptions>
<description xml:lang='en' descriptionType='Abstract'>Background: Monitoring of aggregate, ward-supply data and analysis of the anatomical therapeutic chemical_defined daily dose system, adjusted for bed-occupancy, provides a clear picture of antibiotics consumption frequency and time-trends within hospitals and especially intensive care departments. Material and methods: For this study we used data of a five-year (2010-2014) period, in therapeutic intensive care department of the Emergency Medicine Institute, which show the consumption dynamics of anti-infectives for systemic use of drugs in grams and value indexes. results: The defined daily doses (DDD) per 1000 occupied-bed days (DDD_OBD) of antibiotics in therapeutic intensive care department decreased from 1524 in 2010 to 1206 DDD_1000 in 2014 or by 20.87%, however, it is by 11.77% higher than medium consumption of 1052.25 DDD/1000 in intensive care units with the same activity in international hospitals. The value of 54948 lei per DDD_1000 OBD in 2010 recorded a decline to 40754 lei or by 25.84% in 2014. The cost of one medium DDD from 36.05 lei in 2010 decreased to 33.77 lei or by 6.33% in 2014. The average antibiotics annual institution consumption constituting 464.1 DDD_1000 in 2014 was higher by 1.06% comparatively with medium consumption of 459.20 DDD/1000 registered in 1706 international hospitals, and by 35.31% in comparison with global consumption of 343 defined daily doses per 1000 patient-days. conclusions: The decrease of DDD/1000 OBD and their cost took place as a result of efforts for rational use of antibiotics during the evaluated period. Great opportunities were found for improving rational utilization of anti-infectives for systemic use.</description>
</descriptions>
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<format>application/pdf</format>
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</resource>