Screening toxicologic asupra unui nou compus antimicobacterian, derivat al 5-aril-2-tio-1,3,4-oxadiazolului

Nicolescu Florica; Uncu Andrei; Ancuceanu Robert; Uncu Livia; Ioniță-Mîndrican Corina Bianca; Macaev Fliur; Negreş Simona; Valica Vladimir

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2023-03-26 17:44

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54:615.12 (17)

Химия. Кристаллография. Минералогия (2058)

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NICOLESCU, Florica, UNCU, Andrei, ANCUCEANU, Robert, UNCU, Livia, IONIȚĂ-MÎNDRICAN, Corina Bianca, MACAEV, Fliur, NEGREŞ, Simona, VALICA, Vladimir. Screening toxicologic asupra unui nou compus antimicobacterian, derivat al 5-aril-2-tio-1,3,4-oxadiazolului. In: Revista Farmaceutică a Moldovei , 2014, nr. 3-4, p. 55. ISSN 1812-5077.

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Revista Farmaceutică a Moldovei

Numărul 3-4 / 2014 / ISSN 1812-5077

Screening toxicologic asupra unui nou compus antimicobacterian, derivat al 5-aril-2-tio-1,3,4-oxadiazolului

CZU: 54:615.12

Pag. 55-55

Nicolescu Florica¹, Uncu Andrei², Ancuceanu Robert¹, Uncu Livia², Ioniță-Mîndrican Corina Bianca¹, Macaev Fliur³, Negreş Simona¹, Valica Vladimir²

¹ Universitatea de Medicină şi Farmacie „Carol Davila“,
² Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu“,
³ Institutul de Chimie al AŞM

Disponibil în IBN: 5 ianuarie 2016

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Tuberculoza reprezintă o problemă majoră de sănătate publică. Testarea unor substanţe active noi, cu potenţial antimicobacterian, constituie un obiectiv prioritar al cercetării ştiinţifice la nivel mondial. In acest studiu, ne-am propus ca obiectiv, investigarea profilului toxicologic al unui compus nou sintetizat: 2-(propiltio)-5H-[1,3,4]-tiadiazol[2,3-b] quinazolin5-ona, care a demonstrat o activitate antimicobacteriană remarcabilă in vitro.

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