Objective: To determine relationships between clinical profile, markers of bone metabolism and BMD in postmenopausal women. Methods: A group of 76 postmenopausal women without prior treatment or supplementation for osteoporosis were included. BMI, adiposity index (Durnin & Womersley), BMD at lumbar and hip levels, markers of bone metabolism (β-CTX, osteocalcin), several serum minerals (calcium, zinc, copper, phosphate, magnesium) were measured, with further Pearson correlations evaluation. Results: Significant correlations between the adiposity index and bone metabolism markers were found. Negative relationship with β-CTX (r=0.564, p=0.006) and positive relationship with osteocalcin (r=0.384, p=0.067) were found. Calcium correlated negatively with the adiposity index (r=-0.534, p=0.02), while zinc (r=0.392, p=0.021) and copper (r=0.354, p=0.068) correlated positively with the adiposity index. Lumbar BMD (r=0.611, p=0.000) and hip BMD (r=0.688, p=0.000) correlated positively with the adiposity index. No significant correlations were found with BMI. β-CTX levels revealed positive correlation with calcium (r=0.745, p=0.000) and negative correlations with phosphate (r=0.42, p=0.024), zinc (r=-0.611, p=0.001) and magnesium (r=-0.678, p=0.000). Osteocalcin correlated positively with copper (r=0.745, p=0.000) and negatively with zinc (r=-0.601, p=0.000). Conclusion: The adiposity index (Durnin & Womersley), unlike BMI, has revealed multiple relationships with bonemetabolismmarkers, serum mineral levels and BMD, a higher index being associated with a proanabolic bone profile. Serum phosphate, magnesium and copper were associated with a pro-anabolic bone profile, while serum calcium level was associated with a pro-catabolic bone profile.