The success and failures in the evolution of any country’s economy, including the Republic of Moldova, largely depend on the level of the entities’ development. In this sense, deserve attention the new trends that are manifesting during the last years and affect, in one form or another, the activity of the entities, determining the high complexity of the problems they face. Among the factors with a major impact on the entities, should be mentioned the rapidly changing macroeconomic situation, the market criteria of efficiency, the uncertainty of the legal side of business, etc. In the paper it is addressed the effectiveness of the recently taken measures, which aim is to create more favorable conditions for the development of entrepreneurship in the country. At the same time, the author expresses his own views on the existing deficiencies in this field, including the rationalization of the state control of entrepreneurial activity, the possibility of doing business remotely, the simplification of administrative procedures and the reduction of bureaucracy, etc.