Introduction. Oral suppurations as a starting point from the retropharyngeal space represent a category of rare conditions, but which can lead to very serious complications. The most life-threatening of it can be suffocation on the background of accentuated edema, as well as purulent mediastinitis. Material and methods. The anamnestic, objective, clinical, paraclinical data were taken from medical records. The patients were investigated by laboratory analysis, electrocardiography, medical imaging. The children were consulted and treated multidisciplinary. The specialized literature on similar cases was studied. Results. The patients were treated in the Clinic "Em. Coțaga", ENT Department. During the period of 2018-2023 years, 6 children were treated, of which 5 in the last 12 months. Patients had presented severe clinical symptoms with intoxication syndrome, dyspnea, odynophagia, dysphagia, persistent fever, forced head position, etc. Laboratory analyzes showed: leukocytosis, increased VSH, increased fibrinogen, high CRP. 4 patients required intensive therapy with double or triple antibiotic therapy, rheological, anti-inflammatory, anticoagulant, disaggregating, vitamin therapy. In the first 72 hours 2 persons need consultations. Between 3 and 5 days, 3 patients called for help. After 5 days a patient was admitted and treated. The success rate was 100%, all patients were discharged home in satisfactory condition. Conclusions. Retropharyngeal abscess is a rare condition and is frequently diagnosed in the late stages. To avoid possible complications, the necessary investigations, diagnosis and treatment must be initiated in time, because this pathology can have such complications as: mediastinitis, septicemia, asphyxia, etc.