Introduction. “Post COVID syndrome” or “Long COVID” is a term used to describe the presence of various symptoms, even weeks or months after acquiring SARSCoV-2 infection. Fatigue, cough, chest tightness, breathlessness, anxiety, depression and other clinical manifestations have an important influence on the patient’s functional status and the level of participation in their daybyday activities. Aim of the study: Assessment of Activities of Daily Living (ADL) in people with post COVID syndrome in specialized medical rehabilitation programs. Material and methods. The study included 116 people who endured the mild to moderate forms of SARS Cov-2 infection at an average of 148 days from the acute period. All individuals were included in rehabilitation programs (14 days) with assessment of ADL by applying the Post-COVID-19 Functional Status Scale (PCFS) and the level of depression and anxiety by the Hospital Anxiety and Depression Scale (HADS) until treatment and discharge. Results and discussions. The people included in the study were between 42 and 70 years old, at an average period of 148 days after the acute phase of the disease. According to the PCFS, mild functional limitations were recorded in 53.4%of cases, insignificant - 41.4% and moderate - 5.2% cases with improving for 55.2% of patients with “no functional limitations” on discharge. Borderline cases of anxiety and depression (HADS) were registered at the 71persons before treatment (61.2%), but at discharge, the level of normal psycho-emotional status increasedby13.8%. Conclusions. Specialized medical rehabilitation programs have improved ADLin people with post COVID syndrome by enhancing functional and psycho-emotional status.