The effectiveness of the use of the pro-vitamin preparation β-carotene «Сarolin» in the cultivation of broiler chickens is the goal of our scientific research. Conducted scientific and economic experience was determined: the best result for the studied indicator was obtained in the group in which the drug «Сarolin» appeared in the diet of poultry in a concentration with vitamins A and K3. At the same time, vitamin A was added to the compound feed at a dose equal in biological activity to the amount of the drug «Сarolin», vitamin K3 – the generally accepted norm. It was established that the number of erythrocytes in the blood of experimental chickens increased by 40,2 %, hemoglobin – by 13,1 %, leukopoiesis – by 14,8 %. There was a positive trend in the increase in antioxidants, an increase in the safety of livestock by 2,7 %, an increase in live weight by 7,6 %, a decrease in the cost of feed for live weight gain by 9,1 %, and an increase in the digestibility of crude protein. The output of the gutted carcass of such a bird increased by 11,4 %, the level of amino acids in poultry meat increa-sed by 4,5–5,6 %, and the deposition of vitamin A in the liver increased by 16,0 %. An economic effect has been obtained.