Introduction. Alzheimer's disease is a progressive neurodegenerative disorder of the brain that results in a slow, progressive decline in cognitive function and the appearance of behavioral disturbances, predominantly associated with an age of patients over 65 years. Material and Methods. A synthesis analysis of international publications and specialized literature was performed using Pub Med, Google Academic, Medline, ResearchGATE network, MedScape databases. Results. It has been shown that treatment with cholinesterase inhibitors symptomatically alleviates cognitive and mental disorders. Some researchers have argued the ineffectiveness of the use of antipsychotics in controlling psychosis in dementia, also presenting an increased risk of adverse effects. The performance of Memantine has been confirmed as an alternative treatment in moderate and severe forms, being an antagonist of N-methyl-D-aspartate receptors, it has a stabilizing action in the transmission of nerve signals and improving memory. Studies on anti-amyloid antibody therapy in potentiating the slowing of disease progression have been described, emphasizing the positive results of solanezumab and aducanumab. Conclusion. Currently, there is no specific cure for Alzheimer's disease, but the treatment is pathogenetically and symptomatically oriented, with the assessment of severity, according to the scores presented by the standardized cognitive tests. Early detection of the disease reduces the risk of complications and provides a more favorable prognosis with improved quality of life.