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![]() BOZBEI, Iulia, BENEA, Anna. Iron-chelating activity of poliphenolic extracts. In: Revista de Ştiinţe ale Sănătăţii din Moldova, 2022, nr. 3 An.1(29), p. 474. ISSN 2345-1467. |
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Revista de Ştiinţe ale Sănătăţii din Moldova | ||||||
Numărul 3 An.1(29) / 2022 / ISSN 2345-1467 | ||||||
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Pag. 474-474 | ||||||
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Background. The term „chelation” has been defined as the ability of substances to bind metal ions by forming coordination bonds. Treatment of excess iron by the chelating mechanism has been shown to be effective in reducing the iron content to affordable limits. Objective of the study. Evaluation of the bibliographic sources regarding the study of the iron-chelating activity of phenolic compounds of different medicinal plants. Materials and Methods. Scientific articles from the PubMed platform, Google Scholar, ResearchGate and others have been analyzed to elucidate effective methods of treating diseases caused by excess iron. Results. In the study by S. F. Nabavi et al. (2012) the ethanolic extract of Hyssopus officinalis exhibited the iron-chelating activity of 131.4 mcg/ml in order to reduce concentration of iron ions to 50%. In another study by Ebrahimzadeh et al. (2008) had been calculated the iron-chelating activity of the methanolic extract of aerial parts of Hypericum perforatum of 41%. However, in the study by Armenuhi Moghrovyan et al. (2019) had been studied the iron-chelating activity of the ethanolic extract of aerial parts of Origanum vulgare with the value of 36.7%. Conclusion. Following numerous scientific researches, there were identified plants containing polyphenolic compounds with significant iron-chelating activity and their efficiency in the treatment of excess iron was demonstrated |
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Cuvinte-cheie Iron-chelating activity, Phenolic compounds, excess iron, Activitate de chelare a fierului, Compuşi fenolici, exces de fier |
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