Conţinutul numărului revistei |
Articolul precedent |
Articolul urmator |
224 0 |
SM ISO690:2012 CALISTRU, Iulia, CĂLCÎI, Cornelia, FEGHIU, Ludmila, CALISTRU, Andrei, CONSTANTIN, Olga, HADJIU, Svetlana. Clinical evolution of convulsive status epilepticus in children. In: Revista de Ştiinţe ale Sănătăţii din Moldova, 2022, nr. 3 An.1(29), p. 399. ISSN 2345-1467. |
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Revista de Ştiinţe ale Sănătăţii din Moldova | ||||||
Numărul 3 An.1(29) / 2022 / ISSN 2345-1467 | ||||||
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Pag. 399-399 | ||||||
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Background. Status epilepticus (SE) is one of the most common neurological disorder in children, resulting from the failure of the mechanisms responsible for ending convulsive access or from the initiation of mechanisms, which start prolonged seizures. Objective of the study. An analysis of SE evolution amidst children with new onset seizures and previously pre-established epilepsy, by examining the types of crisis, EEG results and analyzing of the serum concentration of the antiepileptic drugs (AED). Material and Methods. A single-center retrospective trial was conducted between the years 2015-2019. In this study 115 children with convulsive SE, aged between 1 month and 18 years, admitted in the Pediatric Intensive Care Unit were included. Medical records of demographic data, crisis types, EEG results, and serum concentration of AED were analyzed and compared. Results. Among all 115 children with SE, 62.6% (72) were formerly diagnosed with stable epilepsy. In 32.1% of cases, seizures were focal, and 33.04% needed intubation; lethal outcome was in 3.4%. Pathological EEG was found more frequently in children with pre-established epilepsy (p < 0.001). The levels of AED were known in 81% of children with stable epilepsy and 51.6% of them were sub-therapeutic. Conclusion. Stable epilepsy is more common disorder associated with SE. Patients with focal seizures more frequently require intubation. Children with pre-existing epilepsy and SE seem to have more frequently subtherapeutic serum concentrations of AED. |
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Cuvinte-cheie status epilepticus, children, antiepileptic drugs, status epilepticus, copii, remedii antiepileptice |
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