Conţinutul numărului revistei |
Articolul precedent |
Articolul urmator |
239 0 |
SM ISO690:2012 EREMCIUC, Rodica, REVENCO, Ninel, NIKITINA, Irina. Management of growth disorders in children with chronic diseases following the model of idiopathic juvenile arthritis. In: Revista de Ştiinţe ale Sănătăţii din Moldova, 2022, nr. 3 An.1(29), p. 383. ISSN 2345-1467. |
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Revista de Ştiinţe ale Sănătăţii din Moldova | ||||||
Numărul 3 An.1(29) / 2022 / ISSN 2345-1467 | ||||||
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Pag. 383-383 | ||||||
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Background. Juvenile idiopathic arthritis is one of the most common chronic diseases in children. Growth retardation is a common complication in children with juvenile idiopathic arthritis. It is thought to be closely related to disease activity and growth impairment. Objective of the study was to describe the growth velocity, the central and peripheral hormonal profile, as well as the differences between the study subgroups in children with juvenile idiopathic arthritis. Material and methods. 90 patients with a diagnosis of JIA were included. Patients’ evaluation included baseline assessment and follow up on 6, 12 and 18 months. At baseline were assessed general information, JIA characteristics (subtype, disease duration and disease activity), growth parameters and laboratory tests of hypothalamic-hypophysealperipherical axes. Results. General characteristics of the group revealed the average age 9.95 ± 0.49 years, the average age at disease onset 4.31±0.46 years. 14.58 % from patients included in the study presented a growth delay. According to disease subtype, we observed that children diagnosed with systemic onset of JIA are the youngest one and those more affected by growth impairment. Laboratory analysis revealed normal hormonal release at central level, but with abnormalities on peripheral control. No central autoimmune process was detected. All tests for anti-pituitary antibodies were obtained as negative one. Conclusions. Children with juvenile idiopathic arthritis may develop growth disorders. Early diagnosis and good control of disease activity are essential in children with juvenile idiopathic arthritis, which could prevent the adverse effect of the disease on the growth process. |
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Cuvinte-cheie growth, Juvenile idiopathic arthritis, management, children, creşterea, artrită juvenilă idiopatică, management, copii |
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