Conţinutul numărului revistei |
Articolul precedent |
Articolul urmator |
298 1 |
Ultima descărcare din IBN: 2022-12-20 21:28 |
Căutarea după subiecte similare conform CZU |
616.833-009.11-07 (1) |
Инфекционные заболевания. Инфекционные лихорадки (971) |
SM ISO690:2012 MACOVENCIUC, Alina, MATICIUC, Violeta, ODOVENCO, Victor. Variant of Guillain-Barre syndrome in a patient with diffuse large b cell lymphoma: clinical case. In: Revista de Ştiinţe ale Sănătăţii din Moldova, 2022, nr. 3 An.1(29), p. 272. ISSN 2345-1467. |
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Revista de Ştiinţe ale Sănătăţii din Moldova | ||||||
Numărul 3 An.1(29) / 2022 / ISSN 2345-1467 | ||||||
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CZU: 616.833-009.11-07 | ||||||
Pag. 272-272 | ||||||
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Background. Non-Hodgkin lymphoma (NHL) is a malignant tumor that develops from hematopoietic cells located extramedullary. The clinical manifestations of NHL depend on the initial location, the clinical stage, and the morphological type. Guillain-Barré syndrome (GBS) is very rare in NHL. Objective of the study. We present a case of premortem unconfirmed diagnosis of NHL, clinically mimicking GBS. Material and Methods. Anamnesis, clinical and paraclinical data were taken from the medical databases. The patient was investigated by electrocardiography, lung radiography, lung computed tomography, EMG, Nuclear Magnetic Resonance of the brain and of the lumbar spine. Morphopathologically, non-Hodgkin’s lymphoma was demonstrated. Results. The 47-year-old man was admitted with flaccid tetraparesis, oculomotor disturbances, bulbar syndrome, socks and gloves hypoaesthesia, positive Kernig and Lassegue signs. Symptoms assessed up to nadir for two weeks after acute viral infection. EMG was normal. CSF examination revealed proteins 1.028, 283 cells, glucose = 1.57 mmol/l (serum glucose - 4.28mmol/l). Plasmapheresis was performed without a positive effect: aggravation and death on the 15th day of admission. Morphopathologically, diffuse B-cell lymphoma was detected with leucemization and polyorganic damage, including the peripheral nervous system. Conclusion. NHL can be considered in case of presence of clinical manifestations suggestive for GBS, but with inflammatory changes in CSF, the absence of pathological changes in EMG and lack of response to treatment with plasmapheresis. |
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Cuvinte-cheie Guillain-Barre syndrome, non-Hodgkin’s lymphoma, plasmapheresis, Sindrom Guillain-Barré, limfom non-Hodgkin, plasmafereza curativa |
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