Conţinutul numărului revistei |
Articolul precedent |
Articolul urmator |
447 0 |
SM ISO690:2012 ANCUCEANU, Robert, ZBÂRCEA, Cristina Elena, COJOCARU-TOMA, Maria, CALALB, Tatiana, ANGHEL, Adriana-Iuliana, NEGREŞ, Simona, DINU, Mihaela, HOVANET, Marilena. Non-clinical toxicity and phytotoxicity of two herbal extracts. In: Farmacia, 2016, nr. 5(64), pp. 763-769. ISSN 0014-8237. |
EXPORT metadate: Google Scholar Crossref CERIF DataCite Dublin Core |
Farmacia | |
Numărul 5(64) / 2016 / ISSN 0014-8237 | |
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Pag. 763-769 | |
Rezumat | |
Two herbal extracts, one of Panax notoginseng (Burkill) F. H. Chen and the other from oat bran were tested for their toxicity in NMRI mice, Artemia franciscana Kellogg and for their phytotoxicity on Triticum aestivum L. No lethality was recorded and no changes in the parameters followed up were seen for any of the two extracts tested on mice. Based on the experimental data the two extracts may be classified in the Globally Harmonized System (GHS) category 5. In the Artemia test, the Panax notoginseng extract was virtually non-toxic (0% lethality); the oat bran extract had slight toxicity, but for all practical purposes it may also be considered non-toxic. In the Triticum test a concentration-dependent inhibitory effect on root elongation (p < 0.001), was seen at concentrations of 0.5% and higher (p < 0.001% versus control) in the case of Panax notoginseng and at concentrations of 0.25% for the oat bran extract (p < 0.012); the results are in agreement with those seen on Artemia franciscana. |
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