Isopropyl aminomethyl phenol - as an effective disinfectant and bactericidal aganist infectious diseases
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2022-11-27 19:41
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54.05 (57)
Получение, выделение, синтез, очистка и т.п. (51)
SM ISO690:2012
RASULOV, Chingiz, YUSIFOV, Avtandil, DILBAZI, Gulrukh, SHAHMURADOV, Samir, HAMIDOVA, Gulsima, HACIYEVA, Gulsum. Isopropyl aminomethyl phenol - as an effective disinfectant and bactericidal aganist infectious diseases. In: Ecological and environmental chemistry : - 2022, Ed. 7, 3-4 martie 2022, Chișinău. Chisinau: Centrul Editorial-Poligrafic al USM, 2022, Ediția 7, Vol.1, p. 195. ISBN 978-9975-159-07-4.. 10.19261/eec.2022.v1
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Ecological and environmental chemistry
Ediția 7, Vol.1, 2022
Conferința "Ecological and environmental chemistry 2022"
7, Chișinău, Moldova, 3-4 martie 2022

Isopropyl aminomethyl phenol - as an effective disinfectant and bactericidal aganist infectious diseases

CZU: 54.05

Pag. 195-195

Rasulov Chingiz12, Yusifov Avtandil12, Dilbazi Gulrukh12, Shahmuradov Samir12, Hamidova Gulsima12, Haciyeva Gulsum12
 
1 Institute of Petrochemical Processes, National Academy of Sciences of Azerbaijan,
2 Azerbaijan Scientific Research Veterinary Institute
 
 
Disponibil în IBN: 18 martie 2022


Rezumat

All over the world, 35-40% of agricultural products are spoiled and discarded due to diseases and pests. As a result, the yields of the production is fallen down and the biosphere is harmed. Recently, alkylphenols have been used as pesticides, herbicides, insecticides, bactericides, etc. against diseases and pests in agriculture [1,2]. The proposed 4-isopropylaminomethyl phenol is obtained by the interaction of formaldehyde with isopropylamine: The article presents the results of obtaining of Mannich base such as isopropylaminomethyl phenol by the interaction of phenols with isopropyl amine and formaldehyde and study its antibactericidial and disinfectant effect aganist the gut microbes. The aminomethylation reactoin of phenol with isopropylamine was carried out at 80oC and for 2 hrs in the presence of solvent (benzene). As a results, p-isopropylamine methyl phenol was obtained with a yield of 72.3%. The chemical structure of the obtained products were confirmed by IR, NMR spectroscopies. The 1H NMR spectr of 4-isopropylaminomethyl phenol (300 MHz, CDCl3), δ ppm: 1.17(d., 6H, J=6.3Hz), 2.60(s.,1H, NH), 2.92(m., 1H, CH), 3.80(s., 1H, OH), 4.01(s., 2H, CH2), 6.70-7.25(m., 4H, Ar). The 13C NMR spectr of 4-isopropylaminomethyl phenol 13C NMR, δ ppm.: 22.42(CH3), 48.17(CH), 52.95(CH2), 115.47, 116.50, 119.14, 122.96, 128.68, 157.32(C–Ar). The obtained p-isopropylamine methyl phenol was tested as a bactericide and disinfectant aganist coli microbes at the Veterinary Research Institute of Animal of the Ministry of Agriculture of the Republic of Azerbaijan. In the institute, it was proved that aminomethyl phenol among 40 samples presented to the institute showed a positive result. Together with the institute, in the field of application of the isopropylaminemethyl phenol, the Eurasian and Azerbaijan patents were obtained.