The negative impact of the COVID-19 pandemic has been felt by the majority of industries around the world. Although some industries were forced to stagnate, some were partially able to continue their activity, on a small scale. For international tourism, on the other hand, things were completely different. Countries whose GDP is largely based on the annual flow of tourists have suffered economically, and the negative effect was huge. The emergence of rapid tests and mass vaccination of the population offers hope for countries whose economy is based on tourism. In the Republic of Moldova, tourism is poorly developed but has been practically completely affected by the COVID-19 pandemic. Due to the predominant red code in most countries, it has become impossible to travel and also receive foreign tourists. Travel agencies had to postpone all holidays, which caused significant financial losses. At the end of the isolation period, the agents came up with the idea of developing more intensively the national tourism. In 2021, due to the implementation of the safe tourism measures, the number of tourists has changed, but the increasing are only by 2.5% for foreign tourist in 2021.