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![]() CABAC-POGOREVICI, Irina, REVENCO, Valeriu, JITARI, Inessa, MIHALACHE, Georgeta, OCHIŞOR, Viorica. Intrarenal hemodynamics and blood pressure variability in heart failure. In: Cercetarea în biomedicină și sănătate: calitate, excelență și performanță, Ed. 1, 20-22 octombrie 2021, Chişinău. Chișinău, Republica Moldova: 2021, p. 131. ISBN 978-9975-82-223-7 (PDF).. |
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Cercetarea în biomedicină și sănătate: calitate, excelență și performanță 2021 | ||||||
Conferința "Cercetarea în biomedicină și sănătate: calitate, excelență și performanță" 1, Chişinău, Moldova, 20-22 octombrie 2021 | ||||||
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Pag. 131-131 | ||||||
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Background. Blood pressure variability (BPV) has been proved to be promising in providing a great influence on the target organ damage (TOD) and intrarenal circulation. Objective of the study. Thus, the aim of our study is to analyze the complex interconnection between the intrarenal hemodynamics (IRH), TOD and BPV. Material and Methods. We included 30 patients aged 18-75 years, 53% were men and 47% were women. Patients underwent physical examination, blood biochemistry, echocardiography, 24-hours ambulatory blood pressure monitoring (ABPM), intrarenal Doppler obtaining: renal resistive index (RRI), renal pulsatile index (RPI), acceleration time (AT), carotid Doppler ultrasound on internal and common carotid arteries (ICA, CCA) Results. The comparative analysis of nictemeral SBP and DBP variations with IRH parameters revealed that RRI recorded the highest values in night-peakers followed by non-dippers, dippers, whereas the lowest being in extreme dippers (0,679 ± 0,0452 vs. 0,675 ± 0,0373 vs. 0,662 ± 0,0321 vs. 0,641 ± 0,0256, p ˂ 0,01). Similar correlations were assessed for RPI and AT but statistically insignificant (p > 0,05). The comparative analysis of HMOD parameters, left ventricle mass index (LVMI) and the indexed volume of the LA (left atrium) with SBP nictemeral variability patterns showed statistically significant differences in LVMI values that depend upon the assessed profile. Conclusion. The results of our study show the strong connection between IRH, TOD and BPV definitively shifting the paradigm to the complex evaluation of the cardiovascular patient (including ABPM, IRH and the careful evaluation of the TOD). |
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Cuvinte-cheie heart failure, blood pressure variability, intrarenal hemodynamics, insuficienţă cardiacă, variabilitatea tensiunii, hemodinamica intraren |
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