Guillaine-Barre syndrome COVID-19 associated
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616.833.2-002-036:616-036.22:578.834 (1)
Инфекционные заболевания. Инфекционные лихорадки (971)
Вирусология (443)
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CREȚU, Diana, NEDERITA, Mirela, MANOLE, Elena. Guillaine-Barre syndrome COVID-19 associated. In: 7th Congress of the Society of Neurologists Issue of the Republic of Moldova, Ed. 7, 16-18 septembrie 2021, Chişinău. Chişinău: Revista Curier Medical, 2021, Vol.64, p. 38. ISSN 2537-6381 (Online).
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7th Congress of the Society of Neurologists Issue of the Republic of Moldova
Vol.64, 2021
Congresul "7th Congress of the Society of Neurologists Issue of the Republic of Moldova"
7, Chişinău, Moldova, 16-18 septembrie 2021

Guillaine-Barre syndrome COVID-19 associated

CZU: 616.833.2-002-036:616-036.22:578.834

Pag. 38-38

Crețu Diana12, Nederita Mirela12, Manole Elena1
 
1 ”Nicolae Testemițanu” State University of Medicine and Pharmacy,
2 Diomid Gherman Institute of Neurology and Neurosurgery
 
 
Disponibil în IBN: 28 septembrie 2021


Rezumat

Background: Guillain-Barré syndrome (GBS) affects about 100 000 people every year worldwide with the incidence rates of 0.8–1.9 cases per 100000 people annually. A number of case series have reported GBS in association with COVID-19 infection. The aim of our study was to analyse all cases of GBS COVID-19 associated, admitted in a tertiary level neurological hospital. Material and methods: 3 cases with GBS associated with SARS-COV-2 infection were selected. The diagnosis was proved by electromyography (EMG) exam and lumbar puncture. Results: Out of 3, there was 1 female and 2 males with GBS. The registered age was 46, 62 and 67 y.o. Patients developed the disease in 10, 15, and 30 days after the COVID-19 infection. The interval from onset to nadir was 6-9 days. Patients received 5, 10 and 11 points on mEGOS (Modified Erasmus GBS Outcome Score) at day 7 of admission. All patients developed flaccid tetraparesis and “socks” and gloves” sensation loss. Cranial nerves involvement was registered in 2 cases and 2 patients had autonomic disfunction. On EMG, 1 patient was confirmed with axonal polyneuropathy and another 2 with demyelinating polyneuropathy. One patient needed mechanical ventilation. All patients received plasma exchange and 1 benefitted from intravenous immunoglobulins. 1 patient died and other 2 received 4 and 5 points mRS at discharge. Conclusions: GBS COVID-19 associated does not substantially differ from that triggered by other environmental factors.

Cuvinte-cheie
Guillain-Barre syndrome, SARS-CoV-2, demyelinating disease