The article addresses information on prudential regulatory provisions set by central banks in Central and Eastern European (CEE) countries and compares Moldovan versus CEE banking sectors’ prudential experience. Sixteen CEE countries are examined: ten European Union (EU) member-states, two candidates to integration, other four states making part of the Commonwealth of Independent States (CIS). The comparison of prudential requirements in countries from the same region, situated however on rather different development stages, allows to reveal regulatory provisions that may be recommended for implementation in Moldovan banking system. Some of them: improvement of existing deposit insurance scheme, recognition of consolidated supervision’s importance and advisability to address regulatory requirements making part of the Basel II Agreement.