The tourism industry, as a kind of litmus, reflects the slightest changes occurring within the country, but this industry is even more sensitive to external factors. The COVID-2019 pandemic has become such a factor for the tourism business around the world. This article examines the current aspects of the functioning of the tourism industry in Ukraine, analyzes the main factors of the negative impact of the pandemic on the development of the industry, and also discusses measures to reduce its impact on the tourism sector. The emphasis is on studying the transformational changes in the tourism industry caused by anti-epidemiological measures that limit the functioning of this industry under quarantine conditions. The aim of the work is to study the process of adaptation of the tourism industry to the conditions of a pandemic. To achieve this goal, both theoretical and empirical research methods were used.