Analytical investigations on Herring Tissue as a reference material candidate using Instrumental Neutron Activation Analysis (INAA) at the Horia Hulubei National Institute for R&D in Physics and Nuclear Engineering (IFIN-HH) in Bucharest-Magurele are presented in this paper. The sample was supplied by the Institute of Nuclear Chemistry and Technology (INCT), Laboratory of Nuclear Analytical Methods, in Poland in the frame of an international inter-laboratory comparison organized for the certification of trace elements in the marine biota M-3 HerTis sample. Our laboratory contribution to this exercise was based on the results of INAA, with neutron irradiation at the TRIGA reactor in Pitesti, Romania. The results for the following elements were reported: Ag, As, Au, Ba, Br, Ca, Cd, Ce, Co, Cr, Cs, Eu, Fe, Hf, Hg, K, La, Na, Ni, Rb, Sb, Sc, Se, Sm, Sr, Tb, Th, U, Yb, Zn, Zr (31 elements). The elements of certified mass fractions were grouped as: macro constituents of percent (Cl, K, Na, P) and tenths of percent (Mg and S) dry matter contents, as well as trace elements expressed in mg·kg-1 (ppm) (As, Ba, Br, Cu, Fe, Mn, Rb, Se, Sr, Zn) or μg·kg-1 (ppb) (Ag, Cd, Co, Cr, Cs, Hg, Li, Mo, Ni, Pb, Sb, Sc, U, V). Information values were given for Ca, Sm and Y. A comparison of our results against other laboratories and certified values was performed.