| Conţinutul numărului revistei |
| Articolul precedent |
| Articolul urmator |
 639 0 |
 SM ISO690:2012GELMBOLDT, Vladimir, SHYSHKIN, Ivan, ANISIMOV, Vladimir, FONARI, Marina, KRAVTSOV, Victor. Bis(3-hydroxymethylpyridynium) hexafluorosilicate monohydrate as a new potential anticaries agent: Synthesis, crystal structure and pharmacological properties. In: Journal of Fluorine Chemistry, 2020, nr. 235, p. 0. ISSN 0022-1139. DOI: https://doi.org/10.1016/j.jfluchem.2020.109547 |
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  Journal of Fluorine Chemistry |
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| Numărul 235 / 2020 / ISSN 0022-1139 | ||||||
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| DOI:https://doi.org/10.1016/j.jfluchem.2020.109547 | ||||||
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The hexafluorosilicate with the composition (LH)2SiF6·H2O (I, L = 3-hydroxymethylpyridine) was obtained by reaction of 45 % hexafluorosilicic acid with a methanol solution of L (H2SiF6 : L = 3: 1). The crystal structure I is stabilized by OH···O, NH···F, and OH···F H-bonds, and CH···F contacts. The symmetry of the SiF6 2– anion is close to D4 h. The solubility of I in water was 1.63 mol. % and the degree of hydrolysis of the salt in a 1·10–4 M aqueous solution was 91.6 %. A PASS-analysis of the spectrum of biological activity L highlighted a low probability of toxic effects. |
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| Cuvinte-cheie biological activity, Bis(3-hydroxymethylpyridinium) hexafluorosilicate monohydrate, crystal structure, Hydrogen bonds, Solubility |
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