Introduction. HELLP syndrome is a multiple organ dysfunction that occurs in perinatal period, that may cause serious complications and even death. The aim of the study. To assess the complications of HELLP syndrome. Material and methods. A retrospective study was carried out, which included 85 obstetric patients with HELLP syndrome, managed in the Intensive Care Unit during the years 2017-2020. The diagnosis of HELLP syndrome was established based on clinical data (severe preeclampsia, eclampsia, obstetric hemorrhage complications) and laboratory data (thrombocytopenia, increased liver enzymes, hemolysis etc.). The complications were determined based on clinical, paraclinical and laboratory data. Results. The average age of the patients was 28±9.63 years. Primiparous were in 54.65%, multiparous in 45.35% cases, at 25 and 39 weeks of gestation. The patients developed complications as: neurological – central nervous system – 80.8% (cerebral edema – 68.2%, stroke – 4.7% (ischemic – 75%, hemorrhagic – 25%), seizures – 7.7%), visual disturbances (reversible posterior leukoencephalopathy syndrome) – 28.9%, blindness due to retinal detachment – 1.2%), and peripheral nervous system – 76.9% (hyperesthesia – 45.8%, hyperreflexia – 13.5%); pulmonary: acute respiratory distress syndrome – 26%, thrombosis – 21.2% and pulmonary atelectasis – 3.9%; acute kidney injury – 29.4%, anasarca – 96.5%; disseminated intravascular coagulation syndrome – 64.7%; intrauterine growth restriction and fetal death – 70.6%. Conclusion. HELLP syndrome can lead to different complications and multiple organ dysfunctions, that are determined by disseminated microangiopathy, capillary leakage syndrome with anasarca, and increased procoagulant status.