Currently the microbiological industry serves as an important supplier of various amino acids (glutamic acid, lysine, methionine, etc.). Among microorganisms-producers one of the first places is occupied by actinomycetes, in particular, the genus Streptomyces. As a result of microbial relatively environmentally safe synthesis, L-forms of amino acids are produced. The enzymes for amino acid synthesis process can be also obtained by directed microbial synthesis. The subject of the study was the strain Streptomyces fradiae CNMN-Ac-11, isolated from the soil of the central part of Moldova. The culture was stored in two ways: in a lyophilized form and by periodic transfer, using Czapek, Gause and oatmeal agar media. The investigated strain was grown in a liquid medium R with the addition of 0,1% BioR (an extract of amino acids and peptides of Arthrospira platensis). The amino acid composition of the obtained biomass was determined by ion exchange chromatography using the amino acid analyzer AAA-339 M “Microtehna” (Czech Republic). Cultivation of the strain on the changed medium showed an increase in the amount of biomass, total protein and individual groups of amino acids. After addition of BioR at concentration of 0,1% the amount of biomass increased by 18%. In addition, a positive effect of BioR, added to the main medium, on the accumulation of the protein in the biomass was observed. The increase in protein yield was 23,5% compared to the control value. Analysis of the total amino acid content in the Streptomyces fradiae CNMN-Ac-11 biomass showed an increase in the yield of almost all amino acid groups, except for nonessential ones. The increase in the amount of essential amino acids was 78,2%, immunoactive – 14,2%, the amount of glycogenic amino acids increased by 40,6%, ketogenic – by 71,25%, proteinogenic – by 24,3% and sulfur-containing – by 55,5 %. Comparative analysis of the amino acid content in the biomass of Streptomyces fradiae CNMN-Ac-11 cultured on complex medium R with the addition of 0,1% BioR showed a marked increase in the amount of individual amino acids. For example, the amount of threonine increased by 109,26%, serine – by 112,1%, valine – by 102,1%, phenylalanine – by 114,5%, compared to the control sample of biomass. The increase in the amount of amino acids such as cysteine, leucine, isoleucine, lysine, histidine is less pronounced: the yield of cysteine increased by 78,86%, leucine – by 59,6%, isoleucine – by 61,5%, lysine – by 89,5%, histidine – almost 94%. Thus, the obtained data allow considering the bio product BioR for increasing the biosynthetic activity of Streptomyces strains - producers of amino acids.