The fabrication of materials with better qualities relies on the structure of the com-posites that capture the complementary characteristics between all the components of the examined materials. Embedding carbon nanotubes (CNTs) in polymer matrices to obtain composites seems to be a proper method since this kind of filler displays a series of properties which make them required candidates for obtaining superior materials. The final shape of the composites is determined by the arrangement of the CNTs into the matrix and by the interactions provided between components forming the polymer matrix and also interactions between the filler and the matrix. Numerous applications of materials containing CNTs are found in various industrial sectors and more recently in biomedical domains. This work reported fabrication of new composites where both the continuous phase (the polymer matrix) and discontinued phase (particularly, CNTs) are modified. The matrix contains a modified polysulfone while CNTs have been modified with hydroxyl groups to be chemically attached by the matrix. Attenuated total reflection Fourier transform infrared spectroscopy (ATR-FTIR) evidenced the formation of hydrogen interactions between the filler and the matrix. The homogeneity of the samples is observed by Atomic Force Microscopy. The morphological features show the differences that appeared in the structure of the materials after the incorporation of the modified filler. The surface energy of the material was also calculated using the van Oss-Chaudry-Good equation. These parameters are necessary for the required application.