The wine tourism industry faces many challenges that affect sales revenue. These challenges require winemakers to develop measures that will contribute to their financial success. The purpose of the investigation is to research the current situation of the wine tourism of the Republic of Moldova in order to create marketing strategies to improve the profitability of these enterprises and increase the visibility of the wine tourism of the Republic of Moldova at the European level. The present study was carried out based on the following scientific research methods: analysis, synthesis, comparison, grouping, systematization, etc. The applied materials are the studies of various scientific works related to the research topic, the national tourism development program 2026, the activity report of the ONVV, the best practices guide on tourism marketing in the Republic of Moldova. The main results recorded and the contribution of the authors consists in researching the position of the Republic of Moldova in the wine tourism circuit, defining and analyzing the components of marketing strategies, how to develop marketing strategies and SWOT analysis of the activity of wine tourism in the Republic of Moldova. Based on the investigations presented, the authors recommend marketing strategies, which will contribute to the development and improvement of the competitiveness of wine tourism at the level of the Republic of Moldova, at the world level, as well as at the level of any entity that practices or expects to practice this type of activity.