The ecological imbalance between the natural and anthropic ecosystems, the rugged relief, torrential rains, reckless privatization of the agricultural lands, condition the intensification of the soil degradation processes in the Development Regions (North, Center and South) of Republic of Moldova. The land resources in these three regions have a high degree of exploitation of natural resources with consequences on the ecological status. The anthropogenic impact on soil resources, the increase in the number of consumers has led to increased productivity of crops, at the same time this impact has also led to an extreme strain between economic activity and the natural environment, expressed by the depletion of natural resources. During the research period (2007-2021) an in-depth analysis was carried out on the structure of sowing crops used in the Development Regions. As a result of the studies carried out, there was a considerable increase in the share of technical crops both in agricultural enterprises and in peasant households (farmers), which exceeded over 33-43%, and in some districts over 48%-49 %. For example, in the NDR the highest share of technical crops on average for the study period was found in the districts: Briceni (49.4%), Ocnita (49%), Edinet (47.9%), Riscani (46.9%), Dondușeni (44.9%). The average share of areas with technical crops on the NDR is 43.4%. In the districts of the Central Development Region the highest share of areas with technical crops is in the districts: Soldanesti (39,9%), Ungheni (35,5%), Rezina and Nisporeni each 34.3%. In the districts of South Development Region, the highest degree occupied with technical crops constituted 36%-39% for Basarabeasca and Leova districts. In the last years, also the share of areas occupied by hoeing crops has increased considerably. Currently, the share of hoeing crops in the structure of arable land sown with field crops and vegetables in the districts of the Development Regions: North, Center and South has increased on average in till 43.5%-50.4%, but in the Nisporeni, Straseni, districts up till 60%-65%. The increase of the share of hoeing crops in the mentioned Regions, which have a high degree of soil valorization, led to the intensification of erosion processes, to the loss of humus from the soil and to the worsening of the physic-chemical and biological properties of the soil. In different experiments, it has been shown that the cultivation of hoeing crops leads to the acceleration of mineralization processes and the establishment of a negative balance of humus in the soil. Each hectare of such sowings consumes annually, without taking into account erosion, over 1-2 tons of ha. The sown compact crops ranged on average for these three regions between 39%-51%.