Prevention of Chronic Non-Ulcerous Cholitis and the Irritated Intestine Syndrome The lecture offers a contemporary scientific approach of dealing with the so-called irritated intestine syndrome. The problems of incidence, causes, pathogenesis, clinical picture, diagnosis including the laboratory and instrumental procedures are discussed. A complex long-standing and presumptive cause – related treatment is suggested, this being conditioned by the severity of symptoms. The importance of active follow-up examinations as well as the prevention of the irritated intestine syndrome development has been also treated.