Following the Danube, the Prut River is the only internal river where commercial fishing is approved, this activity being carried out in two distinct areas, in the accumulation lake Stânca-Costesti, between 544 km and 742 km, and in the Lower Prut River, from the confluence with the Danube and up to the confluence with the river Elan, between km 0 and km 115. Due to the two very different biotopes, there are significant differences between fishing activity and catches in the accumulation lake Stânca-Costesti and in the Lower Prut River.The fishing activity in the Stânca Costeşti reservoir was registered in the year 2018 by a number of 46 commercial fishermen and in the fishing activity in the lower Prut river were registered in the year 2018 a number of 63 commercial fishermen.The catches recorded in the accumulation lake Stânca-Costesti in 2018 amounted to 22,516 tons, and the ones made in the commercial fishing activity in the lower Prut river in 2018 were 15,325 tons. In the period 2012-2018, the catches recorded in the accumulation lake Stânca-Costesti range from a minimum of 16,595 tons to a maximum of 34,166 tons and in the lower Prut River from a minimum of 11.49 tons to a maximum of 18.42 tons. The structure of catches is also different because the asian ciprinids were captured in considerable quantities in the accumulation lake Stanca-Costesti. Acknowledgement: The study was performed within the project with code BSB165– HYDROECONEX.