After becoming one of the most significant parts of modern economy as well as a main element of market economy, trade is strategically important for the sustainable development of the society. In terms of modern economy trade is also imperative for a balanced and sustainable development of any economic system. Changes occurring in this branch over the past two decades contributed to trade liberalization, trade entrepreneurship development, activity extension, and certain deficiencies have emerged at the same time: normative, legislative, organizational, managerial, consumer protection, etc. The aim of this paper is to highlight domestic trade issues in the Republic of Moldova and to propose solutions for their recovery. This paper analyses the current situation regarding domestic trade and its positioning within the socioeconomic system, as well as the challenges encountered. Based on this analysis, strategic objectives for the development of domestic trade have been pointed out. The study was performed employing a large array of research tools. The research results obtained have provided support for the development of Domestic Trade Development Strategy for 2014-2020 period, under implementation.