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SM ISO690:2012 CALCII, Cornelia, SPRINCEAN, Mariana, LUPUŞOR, Nadejda, FEGHIU, Ludmila, REVENCO, Ninel, HADJIU, Svetlana. Clinical features of status epilepticus in children. In: Perspectives of the Balkan medicine in the post COVID-19 era: The 37th Balkan Medical Week. The 8th congress on urology, dialysis and kidney transplant from the Republic of Moldova “New Horizons in Urology”, Ed. 37, 7-9 iunie 2023, Chişinău. București: Balkan Medical Union, 2023, Ediția 37, p. 249. ISSN Print: ISSN 1584-9244 ISSN-L 1584-9244 Online: ISSN 2558-815X. |
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Perspectives of the Balkan medicine in the post COVID-19 era Ediția 37, 2023 |
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Congresul "Perspectives of the Balkan medicine in the post COVID-19 era" 37, Chişinău, Moldova, 7-9 iunie 2023 | ||||||
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Introduction. The aim of this research was evaluation of clinical and etiological profile of refractory status epilepticus (RSE) among children. Status epilepticus is defined as a neurologic emergency in which there is at least 5 minutes of seizure activity or recurrent seizures with a return to baseline between seizures. Material and methods. We performed a study that has been done between 2019 -2022. All children were admitted with convulsive status epilepticus (SE), with evolution in RSE (refractory status epileptic). We try to identify the main characteristics of children with RSE and those without an evolution in RSE. Results. 55 children, out of whom 32 boys with SE were enrolled in the study, of which 20 children (36%) developed RSE. CNS infections were the most common causes in SE and development of RSE (51% in SE and 53% in RSE, p > 0.05). Noncompliance of antiepileptic medication served as the second cause for evolution in RSE. The overall mortality rate was 10.9%, the chances of death in RSE (20%) being higher than in SE (5.7%). The unfavorable prognosis was seven times higher in children with RSE, compared to children who developed SE (PR= 7.0; 95% CI :1.6-22.3). Conclusions. In the management of CNS infections, pediatricians should be aware of the high risk of developing RSE. In addition, the possibility of developing RSE should be considered and promptly managed in an intensive care unit in order to reduce the risk of mortality and morbidity of this severe neurological condition. |
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