The paper presents the results of preliminary research on the need for functional-adaptive clothing for people with disabilities caused by breast cancer. The study includes identification of disability impact factors, data analysis on the incidence of breast cancer, and analysis of data on new cases of breast cancer by age group. The work aims to establish the initial data needed for the process of structural and technological design of functional clothing products intended for people with disability of breast cancer-related diseases. The relevance of the topic is determined by the problems that arise as a result of post-mastectomy, and the interest of women after mastectomy in their appearance, as well as the comfort determined by the fashion product, especially in matching clothing with external breast prostheses. The paper mentions factors for determining disability among patients with breast cancer. One of the problems that are being tried to be solved in this work is to determine the age and gender group with the highest incidence of breast cancer and the degree of disability caused by oncological pathology of breast tissue. It is recommended to use the results of the preliminary study as source data in the development of functional-adaptive clothing products intended for people with disabilities caused by breast cancer.