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Ultima descărcare din IBN: 2023-09-12 08:02 |
SM ISO690:2012 ŞTÎRBA, Olga, TAGADIUC, Olga, ANDRONACHE, Lilia, SARDARI, Veronica, GUDUMAC, Valentin. Influenţa compuşilor coordinativi ai cuprului asupra activităţii proteazelor lizozomale renale la şobolani adulţi. In: Analele Ştiinţifice ale USMF „N. Testemiţanu”, 2012, nr. 1(13), pp. 141-146. ISSN 1857-1719. |
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Analele Ştiinţifice ale USMF „N. Testemiţanu” | ||||||
Numărul 1(13) / 2012 / ISSN 1857-1719 | ||||||
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Pag. 141-146 | ||||||
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Influence of the copper coordination compounds on the activity
of renal lisosomal proteases în adult rats
The aim of the study was to investigate the influence of copper coordination compounds CMT-28, CMT-67 and their combinations with the cyanobacterial remedy BioR on the activity of lysosomal proteases (LP) in the kidneys of intact rats. It was established that all substances studied differently influence the activity of cathepsines D, G, L, H, B and leucineaminopeptidase in male and female rats. CMT-67 shows the highest increase of LP renal activity, and the combination with BioR only induces a significant increase of cathepsine H activity. CMT-28 slightly enhances the renal activity LP and the combination with BioR does not potentiate this effect. |
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