Conţinutul numărului revistei |
Articolul precedent |
Articolul urmator |
215 0 |
SM ISO690:2012 SECU, Gheorghe, ROȘCA, Tamara, VERDEȘ, Daniela. Anticoagulation therapy in pregnant women with mechanical heart valve. In: Revista de Ştiinţe ale Sănătăţii din Moldova, 2022, nr. 3 An.1(29), p. 421. ISSN 2345-1467. |
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Revista de Ştiinţe ale Sănătăţii din Moldova | ||||||
Numărul 3 An.1(29) / 2022 / ISSN 2345-1467 | ||||||
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Pag. 421-421 | ||||||
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Rezumat | ||||||
Background. Patients with mechanical valves require lifelong anticoagulant therapy. A special category of these patients are pregnant women in whom the thromboembolic risk is increased, and the selection of drug therapy must also take into account the perinatological results. Objective of the study. Evaluation of current recommendations in the management of pregnant women with mechanical valve prostheses. Material and Methods. Bibliographic revision of the recommendations and guidelines of WHO, ACOG, ACCP, ESC, AHA, JCS, SBC regarding the anticoagulant management of pregnant women with mechanical valve prostheses. Results. Pregnant women with mechanical valve prostheses fall into class 3 according to the WHO for cardiovascular risk. Although coumarin derivatives are the most effective drugs in preventing thromboembolic complications, more than 40% of pregnancies will be compromised when used in the first trimester. Careful planning of pregnancy, switching to heparin therapy up to 13 weeks of gestation, and subsequent conversion to coumarin derivatives in the hospital is recommended. In cases of increased thromboembolic risk continuous treatment with coumarin derivatives including in the first trimester is recommended. At 34-36 weeks of gestation, conversion to heparin therapy in the hospital, until birth, with subsequent conversion to coumarin derivatives. Conclusion. Pregnant women with valve prostheses require close monitoring by the obstetrician and cardiac surgeon with the application of individualized anticoagulant regimens. The conversion from one class of drugs to another will be done only in the hospital under strict supervision. |
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Cuvinte-cheie pregnancy, valve prostheses, Anticoagulants, sarcina, proteze valvulare, anticoagulante |
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