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616.24-002.5+612.017]-053.2 (3) |
Patologia sistemului respirator. Tulburări ale organelor de respiraţie (765) |
Fiziologie. Fiziologie umană și comparată (733) |
SM ISO690:2012 BANDALAC, Cătălina, BOUNEGRU, Anastasia, CRANGACI, Marin. Pediatric tuberculosis in relation to BCG vaccine. In: Revista de Ştiinţe ale Sănătăţii din Moldova, 2022, nr. 3 An.1(29), p. 232. ISSN 2345-1467. |
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Revista de Ştiinţe ale Sănătăţii din Moldova | ||||||
Numărul 3 An.1(29) / 2022 / ISSN 2345-1467 | ||||||
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CZU: 616.24-002.5+612.017]-053.2 | ||||||
Pag. 232-232 | ||||||
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Background. BCG immunization gives the child a safe immunity to prevent the severe forms of tuberculosis (TB) by activation of macrophages and the process of phagocytosis. This requires the success of the treatment of the child with tuberculosis. Objective of the study. Evaluation of the peculiarities of the evolution of TB in children unimmunized with BCG and the effectiveness of treatment. Material and Methods. A sample of 41 cases of TB was examined in children unimmunized with BCG, hospitalized in the children’s department of IMSP SCMF. The particularities of the evolution and the effectiveness of the treatment were evaluated. Results. The sample included 19 boys (46%) and 22 girls (54%), 31 (76%) children being of „phthisiogenic” age. The contraindications for BCG vaccination had 14 (35%), the refusal of parents to immunize with BCG was in 12 (29%) cases, 6 (15%) children were born in countries without BCG vaccine in the vaccination scheme. From the tuberculosis outbreak, 31 (75%) children were diagnosed, based on clinical and radiological data 10 (25%) cases were diagnosed. Intrathoracic lymph node TB was established in 28 (68%) children, pulmonary forms of TB – in 13 (32%) children, infiltrative pulmonary TB with pleural effusion and dissemination was detected in 6 (15%) adolescents. One 1 (2%) child had HIV coinfection. Persistent febrile syndrome and rare dry cough have outlined the clinical manifestations. Treatment for sensitive TB was administered in 37 (91%), for resistant TB – in 4 (9%) cases. Treatment was successful in 39 (95%) cases. Conclusion. Children who are not vaccinated with BCG are at risk for TB at an early ag |
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Cuvinte-cheie BCG vaccine, tuberculosis, children, vaccin BCG, tuberculoza, copii |
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