Pulmonary embolism in the cardiovascular diseases : anatomo –clinical study on 12 years 1999-2013
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PARASCAN, Liliana. Pulmonary embolism in the cardiovascular diseases : anatomo –clinical study on 12 years 1999-2013. In: Archives of the Balkan Medical Union Supliment, 2013, nr. S3(48), p. 99. ISSN 0041-6940.
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Archives of the Balkan Medical Union Supliment
Numărul S3(48) / 2013 / ISSN 0041-6940

Pulmonary embolism in the cardiovascular diseases : anatomo –clinical study on 12 years 1999-2013


Pag. 99-99

Parascan Liliana
 
Emergency Institute Of Cardiovascular Diseases”Prof. Dr. C.C. Iliescu”, Bucharest
 
 
Disponibil în IBN: 2 noiembrie 2022


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Aim: among the causes of sudden deaths (SD) we now proposed to treat pulmonary thromboembolism (PTE) from the anatomo- clinical perspective in order to appreciate its importance on necroptic cases of our Clinic. Material and methods: the material studied is represented by the necropsies performed in our clinic between 1999-2013 that showed clinically and pathologically pulmonary embolism. As etiology PTE originates from lower limbs veins (the most frequently) and from pelvic veins. As a physio-pathological mechanism: mechanical obstruction of a pulmonary vessel releasing reflex vasoconstriction. Clinically: chest pain, dyspnea, “climbing” pulse; first and sole syncope manifestation (14%); 50% of serious forms have no prodromal syndrome; in 1/3 of the lethal cases death occurs in the first hour ;at autopsy thrombi of variable sizes in lung arteries. Studied patients were examined anatomo-pathologically being performed necropsies in the above mentioned period and being examined histologically fragments of lungs with pulmonary artery thromboses. Colorations were performed: HE, VG, Gomory, Alcian blue. Results: From a total of 738 necropsies so far performed in our Clinic, a total of 57 had pulmonary embolism as leading intermediate cause of death . Age range at which death occurred was between 9 and 80 years. Gender distribution was 17 females and 40 males. Important associated comorbidities that could trigger TEM through pelvic thromboses or of the lower limbs were: congenital cardiovascular malformations - 2 cases (Tetralogy of Fallot and Interatrial Septal Deffect type foramen secundum), cardiovascular surgery - 5 cases, dissection of the aorta - 8 cases, states sepsis (endocarditis, bronchopneumonia) - 7 cases, thrombosis of the legs - 7 cases, acute myocardial infarction - 8 cases, dilated cardiomyopathy - 12 cases, left ventricular hypertrophy - 6 cases, advanced TB lesions (as bronchopneumonia, miliaria, cavern) - 4 cases, tumors (gastric, pancreatic, lung AK) - 3 cases. Of all cases with PTE in 35.19% of them was also found adjacent recent pulmonary infarction. Conclusions: Out of necroptic cases pulmonary thromboembolism (PT) represented 7.35%, being situated among the most common causes of sudden death that may occur in pulmonary cardiovascular pathology as leading intermediate cause of death [b] as a complication of initial condition [c)] ,which finally led to cardio-respiratory failure from acute immediate cause of death [a)].

Cuvinte-cheie
pulmonary embolism, cardiovascular diseases, anatomo-clinical study