In medical practice, early diagnosis of CT is difficult because the neoplasm coexists or develops against the background of nodular-inflammatory thyroid pathologies, which have a slow evolution, CT is often associated with thyroiditis. The association of thyroid carcinoma with autoimmune thyroiditis remains debatable. In the literature, this combination is noted in 1% to 75% of cases. In recent years, there has been a steady increase in the number of thyroid cancers developed against the background of autoimmune thyroiditis, this being explained by improved diagnostic methods, living environment and increasing the number of elderly people. The relationship between inflammation and cancer is known to be that patients with autoimmune thyroiditis have a higher risk of developing thyroid cancer. The literature does not fully elucidate the hormonal peculiarities of thyroid cancer associated with autoimmune thyroiditis have not been studied yet in the Repulic of Moldova Motivation: The hormonal peculiarities of thyroid cancer associated with autoimmune thyroiditis have not been studied yet in the Republic of Moldova. Method: In order to analyze the hormonal manifestations, the patients were preoperatively collected tests for hormones from the venous blood. Results: In thyroid cancer associated with autoimmune thyroiditis as well as patients in the control group have in most cases normal values of T3 and T4. The TSH value is within the norm in most patients included in the study in both the research group and the control group, and the increased value of the TSH index was observed more in patients with thyroid carcinoma associated with autoimmune thyroiditis. We conclude that thyroid cancer associated with autoimmune thyroiditis in most cases is accompanied by the increased antiTPO marker. Conlusions: Thyroid cancer associated with autoimmune thyroiditis in most cases occurs with the increased antiTPO and TSH.