Conţinutul numărului revistei |
Articolul precedent |
Articolul urmator |
393 0 |
SM ISO690:2012 DINU, Maria Valentina, GRĂDINARU, Adina-Catinca, LAZAR, Maria Marinela, DINU, Ionel Adrian, RASCHIP, Irina Elena, CIOCARLAN, Nina, APROTOSOAIE, Ana-Clara. Physically cross-linked chitosan/dextrin cryogels entrapping Thymus vulgaris essential oil with enhanced mechanical, antioxidant and antifungal properties. In: International Journal of Biological Macromolecules, 2021, nr. 184, pp. 898-908. ISSN 0141-8130. DOI: https://doi.org/10.1016/j.ijbiomac.2021.06.068 |
EXPORT metadate: Google Scholar Crossref CERIF DataCite Dublin Core |
International Journal of Biological Macromolecules | |
Numărul 184 / 2021 / ISSN 0141-8130 /ISSNe 1879-0003 | |
|
|
DOI:https://doi.org/10.1016/j.ijbiomac.2021.06.068 | |
Pag. 898-908 | |
Rezumat | |
Herein, we entrapped Thymus vulgaris essential oil (EO) within the physically cross-linked sponge-like architecture of cryogels by ice template-assisted freeze-drying. Their 3D cryogenically-structured network was built through hydrogen bonding formed by blending two naturally-derived polysaccharides, chitosan and dextrin. The embedment of EOs within the cryogel matrix generates porous films with an increased elasticity that allows their fast shape recovery after full compression. Thus, the swollen EOs-loaded cryogel films exhibited an elastic modulus of 3.00 MPa, which is more than 40 times higher than that of polysaccharide films without EOs (an elastic modulus of only 0.07 MPa). In addition, the encapsulation of bioactive compounds endows the bio-based films with both antioxidant and antifungal properties, showing a radical scavenging activity of 65% and a zone inhibition diameter of 40 mm for Candida parapsilosis fungi. Our results recommend the entrapment of EOs into bio-based cryogel carriers as a straightforward approach to provide ‘green’ polysaccharide-based films having both improved physicochemical properties and remarkable antifungal activity. |
|
Cuvinte-cheie biological properties, chitosan, Dextrin, Physically cross-linked cryogels, Shape recovery ability, Thyme essential oil |
|
|
DataCite XML Export
<?xml version='1.0' encoding='utf-8'?> <resource xmlns:xsi='http://www.w3.org/2001/XMLSchema-instance' xmlns='http://datacite.org/schema/kernel-3' xsi:schemaLocation='http://datacite.org/schema/kernel-3 http://schema.datacite.org/meta/kernel-3/metadata.xsd'> <identifier identifierType='DOI'>10.1016/j.ijbiomac.2021.06.068</identifier> <creators> <creator> <creatorName>Dinu, M.</creatorName> <affiliation>Institutul de Chimie Macromoleculara „Petru Poni“, Iaşi, România</affiliation> </creator> <creator> <creatorName>Grădinaru, A.</creatorName> <affiliation>Universitatea de Medicină şi Farmacie „Gr.T. Popa“, Iaşi, România</affiliation> </creator> <creator> <creatorName>Lazar, M.</creatorName> <affiliation>Institutul de Chimie Macromoleculara „Petru Poni“, Iaşi, România</affiliation> </creator> <creator> <creatorName>Dinu, I.</creatorName> <affiliation>Institutul de Chimie Macromoleculara „Petru Poni“, Iaşi, România</affiliation> </creator> <creator> <creatorName>Raschip, I.</creatorName> <affiliation>Institutul de Chimie Macromoleculara „Petru Poni“, Iaşi, România</affiliation> </creator> <creator> <creatorName>Ciocîrlan, N.G.</creatorName> <affiliation>Grădina Botanică Naţională (Institut) "Alexandru Ciubotaru", Moldova, Republica</affiliation> </creator> <creator> <creatorName>Aprotosoaie, A.</creatorName> <affiliation>Universitatea de Medicină şi Farmacie „Gr.T. Popa“, Iaşi, România</affiliation> </creator> </creators> <titles> <title xml:lang='en'>Physically cross-linked chitosan/dextrin cryogels entrapping Thymus vulgaris essential oil with enhanced mechanical, antioxidant and antifungal properties</title> </titles> <publisher>Instrumentul Bibliometric National</publisher> <publicationYear>2021</publicationYear> <relatedIdentifier relatedIdentifierType='ISSN' relationType='IsPartOf'>0141-8130</relatedIdentifier> <subjects> <subject>biological properties</subject> <subject>chitosan</subject> <subject>Dextrin</subject> <subject>Physically cross-linked cryogels</subject> <subject>Shape recovery ability</subject> <subject>Thyme essential oil</subject> </subjects> <dates> <date dateType='Issued'>2021-08-01</date> </dates> <resourceType resourceTypeGeneral='Text'>Journal article</resourceType> <descriptions> <description xml:lang='en' descriptionType='Abstract'><p>Herein, we entrapped Thymus vulgaris essential oil (EO) within the physically cross-linked sponge-like architecture of cryogels by ice template-assisted freeze-drying. Their 3D cryogenically-structured network was built through hydrogen bonding formed by blending two naturally-derived polysaccharides, chitosan and dextrin. The embedment of EOs within the cryogel matrix generates porous films with an increased elasticity that allows their fast shape recovery after full compression. Thus, the swollen EOs-loaded cryogel films exhibited an elastic modulus of 3.00 MPa, which is more than 40 times higher than that of polysaccharide films without EOs (an elastic modulus of only 0.07 MPa). In addition, the encapsulation of bioactive compounds endows the bio-based films with both antioxidant and antifungal properties, showing a radical scavenging activity of 65% and a zone inhibition diameter of 40 mm for Candida parapsilosis fungi. Our results recommend the entrapment of EOs into bio-based cryogel carriers as a straightforward approach to provide ‘green’ polysaccharide-based films having both improved physicochemical properties and remarkable antifungal activity. </p></description> </descriptions> <formats> <format>uri</format> </formats> </resource>