The transition period of the Republic of Moldova towards a competitive economy and an efficient public administration implies a series of phenomena and significant changes of the political, socio-economic and cultural paradigms and, not the least, in public administration, which faces a series of transformation regarding its functionality in relation to the expectations from the political elite and citizens, of the economic sector and also the attributions, responsibilities and ranking of the performance sources. In Moldova, the reform of the central administration is often addressed in the political talks, studies, scientific communities, but only few researchers and experts are delivering solutions, strategies and personal opinions. This article introduces an outlook of the optimal structure of the government in the Republic of Moldova in the context of the public administration reform.