The method of long-term preservation of mammalian semen in deep-frozen condition provides great opportunities for development and improvement of the reproduction system of farm animals. Using this method it is possible to check the breeders on the quality of offspring so as to maximum use the improvers. This allows performing the large-scale genetic selection in animal husbandry, which significantly increases the rate of mass improvement of breeding and productive qualities of animals. However, the existing cryotechnology not provide maximum preservation of the biological integrity of the reproductive cells. Comprehensive research has shown the possibility of increasing the efficiency of cryopreservation by improving of synthetic mediums and the development of optimum cryopreservation process parameters.