Water-soluble metallphthalocyanine grafted copolymers and their further application perspective
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TIULEANU, Pavel. Water-soluble metallphthalocyanine grafted copolymers and their further application perspective. In: Sesiune națională cu participare internațională de comunicări științifice studențești, Ed. 24, 15 februarie 2020, Chișinău. Chișinău, Republica Moldova: Centrul Editorial-Poligrafic al USM, 2020, Ediția 24, Vol.1, pp. 21-23. ISBN 978-9975-142-89-2.
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Sesiune națională cu participare internațională de comunicări științifice studențești
Ediția 24, Vol.1, 2020
Sesiunea "Sesiune naţională de comunicări ştiinţifice studenţeşti"
24, Chișinău, Moldova, 15 februarie 2020

Water-soluble metallphthalocyanine grafted copolymers and their further application perspective

CZU: 678.7:577.1:615

Pag. 21-23

Tiuleanu Pavel
 
Moldova State University
 
 
Disponibil în IBN: 8 mai 2020


Rezumat

Nowadays, due to many problems associated with various diseases, such as cancer, the optimization of the production and use of elec­tri­ci­ty and other types of household issues, polymer chemistry is gaining wi­der horizons for application. This study examined copolymers ba­sed on water-soluble forms of zinc phthalocyanine. Transition metal phtha­­lo­cyanines are known to have pronounced photosensitive pro­per­ties, which are used in the prevention of tumor diseases in PDT, and also manifest themselves as bactericidal agents in various compo­si­tio­nal compounds with water-soluble polymers [2].The beneficial qualities of phthalocyanines cannot be fully utilized due to their lack of solubility in various organic solvents, as well as its complete absence in water. This problem was solved by us after obtai­ning a water-soluble form of zinc phthalocyanine with a copolymer of acrylic chloride and N-vinylpyrrolidone, which is non-toxic and so­luble in water, which also allows us to suppose it to be used it in many areas of medicine, as well as to improve the properties we need, with the proposed formation of zinc tetravinyloxyphthalocyanine (Image) [1, 3].figureImage. Synthesis of the copolymer of N-vinylpyrrolidone with zinc vinyloxyphthalocyanine:1) Synthesis of copolymer of N-vinylpirrolidone and acrylic chloride;2) Grafting the obtained polymer with zinc phthalocyanine The obtained compound was tested with the prospect of using in PDT [4], but most important are studies of its bactericidal properties, car­ried out on some groups of bacteria, such as S. Aureus, S. Epi­der­malis, S. Aeruginosa, Acinetobacter Baumani. Due to obtained water-so­lubility of compound, there are many further ways to study it, with the prospects of its use in medicine.