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 SM ISO690:2012ŞTIRBU, Eugeniu, COSTIŞ, Tatiana, ŢURCANU, Parascovia, ŢÂBÂRNĂ, Victoria. Impactul stresului postnatal timpuriu asupra comportamentului explorativ şi a capacităţilor cognitive generale la şobolani. In: Fiziologia şi sănătatea, 27-28 septembrie 2012, Chișinău. Chişinău Republica Moldova: Institutul de Fiziologie şi Sanocreatologie al AŞM, 2012, pp. 377-383. ISBN 978-9975-62-323-0. |
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| Fiziologia şi sănătatea 2012 | ||||||
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Congresul "Fiziologia şi sănătatea" Chișinău, Moldova, 27-28 septembrie 2012 | ||||||
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The aim of article is to elucidate the impact of chronic stress (maternal separation, about 3 h, 10 days) at different stages of early postnatal development on exploratory behavior and general cognitive capacity at puberty. It was shown that stressed rats in early postnatal ontogenesis, at puberty was affected exploratory behavior, which showed by essential decrease of motor activity in open fi eld, especially in center of fi eld, and by reduced exploring of a new object appeared in the known entourage of animal, have general cognitive disorders, which were manifested by the inability to solve the problem of acquiring food in “syringe” test, compared with control rats. It was found that mental defects were more severe in stressed rats on postnatal days 3-12, than on days 13-22. Conclusion is that stress in early postnatal ontogenesis |
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| Cuvinte-cheie early postnatal stress, exploratory behavior, open fi eld, new object, general cognitive ability |
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