Analysis of geological and geophysical data in the center of Republic of Moldova territory, along the Leova and Chisinau cities geologic profile, allows to develop new geophysical model, which reflects the local soil conditions by reference parameters: density, velocity of seismic wave and quality factor. The geological reference levels setting are based on 50 boreholes, with 200-2500m depth, in which the Cenozoic, Maesozoic, Paleozoic, and sedimentary formations of Precambrian as Proterozoic and Archeozoic were identified. The Precambrian (Proterozoic and Archean) sedimentary layers forms the crystalline foundation of the Moldovian Platform. The Cenozoic and Paleozoic formation thickness tends to increase on West direction, whereas Proterozoic and Mesozoic horizonts keeps a constant level of sendimentation along the profile. Based on the level of laying for crystalline foundation of the platform, this new geophysical model of the investigated area can be connected with regional models for a subsequent application in the study of seismic hazard in Republic of Moldova territory.