Synthesys of a functionalized furan fragment through bromination-cyclization of a conjugated diene
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KULCIŢKI, Veaceslav, CARA, Marina, BOURDELAIS, Andrea, SCHUSTER, Tomas, BADEN, Daniel. Synthesys of a functionalized furan fragment through bromination-cyclization of a conjugated diene. In: Chemistry Journal of Moldova, 2010, nr. 1(5), pp. 118-120. ISSN 1857-1727.
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Chemistry Journal of Moldova
Numărul 1(5) / 2010 / ISSN 1857-1727 /ISSNe 2345-1688

Synthesys of a functionalized furan fragment through bromination-cyclization of a conjugated diene

Pag. 118-120

Kulciţki Veaceslav1, Cara Marina1, Bourdelais Andrea2, Schuster Tomas2, Baden Daniel2
 
1 Institute of Chemistry of the Academy of Sciences of Moldova,
2 Center for Marine Science, University of North Carolina Wilmington
 
 
Disponibil în IBN: 2 decembrie 2013


Rezumat

This paper describes the use of a terpenic model substrate to conjugate 1,4-additions of N-bromosuccinimide (NBS) to a diene system possessing a suitable oxygen functionality. The reaction leads to functionalized tetrahydrofuran derivatives, which can be developed further into different synthetic targets, such as polyethers, which are known to possess diverse biological activity.

Cuvinte-cheie
terpenoids, furans,

NBS, conjugate addition