In all times, the welfare of nation was generated by the gross internal product’s level, which represents „the gross value of the final production of goods and services produced, in a specific period of time, by the economical agents which activates between the national borders”. The gross internal product’s growth is desirable in any country because it gives to population the possibility to consume more goods and services and in the same time it contribute to the insurance of a big quantity of goods and social services, like health, education etc., generating in this way a real grow of the life quality. It is interesting to study the evolution of gross internal product in Moldova and its dependence and basic factors using correlation analysis. As the basic factors explaining the evolution of the gross internal product, the factors were selected: number of viable enterprises, investments in fixed assets, foreign investments in the social capital, final consumption, total export. The simulation was performed through the QM computing software and the multiple regression equation expressing the dependence of the gross internal product on the selected factors was obtained. The calculated regression equation can serve to predict the value of gross internal product in the Republic of Moldova, knowing the planned values of the factors included in this equation. A significant increase in gross internal product can be achieved by: increasing consumption in the Republic of Moldova, increasing investments in fixed assets, increasing the number of enterprises and increasing export. Estimating of the regression coefficients and of the correlation coefficient has shown that the values of these coefficients are considerable and the conclusions reached are credible.